Biological Regulation and Development: Hormone Action by Abraham White, Rachmiel Levine (auth.), Robert F.

By Abraham White, Rachmiel Levine (auth.), Robert F. Goldberger, Keith R. Yamamoto (eds.)

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Extra info for Biological Regulation and Development: Hormone Action

Sample text

Given the present state of our knowledge, I believe that we must turn our attention to physics to find the clues to the dynamic analysis of living systems. To prepare for such considerations, I next turn to the philosophy and the physics of complex systems. 1 Philosophical Foundations of the Study of Complex Systems Complexity Complexity is not well defined, and neither is simplicity (Pattee, 1977). In Table II, I have listed eight somewhat interrelated attributes that in various combinations convey TABLE II.

The linguistic analysis will be shown to be uniquely the province of biology itself. It is the part of biology that cannot yet be reduced to physical theory, and perhaps never will be. In Section 2 of this chapter I discuss aspects of engineering systems analysis and control theory. In Section 3 I present philosophical foundations for systems analysis. Section 4 introduces the physics of complex systems. These three sections comprise the background for the analysis. FRANCIS EUGENE YATES Angeles, California 90024 • Crump Institute for Medical Engineering, University of California, Los 25 2 26 FRANCIS EUGENE YATES Section 5 takes the reader on a "zoom-lens" tour through the metabolic system of a human being, from his ingestive behavior down to the modulation of phase changes in a multi subunit, junctional protein by calcium ions.

Polak, J. , Pearse, A. G. , Bloom, S. , 1975, Growth hormone releaseinhibiting hormone in gastrointestinal and pancreatic D. cells, Lancet 1:1220. Putnam, T. , Benedict, E. , and Teel, H. , 1929, Studies in acromegaly. Experimental canine acromegaly produced in injection of anterior lobe pituitary extract, Arch. Surg. (Chicago) 18:1708. , Bates, R. , and Dykshorn, S. ]' Physiol. 105:191. Rolleston, H. , 1936, The Endocrine Glands in Health and Disease with an Historical Review, Oxford University Press, London.

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