A Research Annual by Paul M. Wassarman (Eds.)

By Paul M. Wassarman (Eds.)

The inaugural quantity of Advances in Developmental Biology and Biochemistry paints a slightly huge stroke throughout the box. development formation and mobile conversation in the course of animal improvement, in addition to Y chromosome functionality in the course of mammalian improvement, are significant topics of this quantity. numerous experimental platforms, together with mice, flies, and worms are thought of.

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10). This phenotype was shown to result even when injections were performed at the 8-16-cell stage and occurred irrespective of the site of injection in the egg. Mutation of a single conserved cysteine residue abolished bifurcation, adding credence to the functional significance of these invariant amino acid residues. Bifurcation was also abolished by removal of sequences encoding the signal peptide but restored by the addition of unrelated sequences encoding a signal peptide from chick lysozyme (McMahon and Moon, 1989b).

Tokunaga. , and Sugie, T. (1985) Altered sex ratio of live ywng after transfer of fast- and slowdeveloping mouse embryos. Gamete Reseatrh 12:Ml-304. Vigier. , Ghaffari, S.. and J~sso,N. (1989) Endocrine sex-reversal of the fetal ovary: a quantitative bioassay for anti-Miillerian activity. In: Development and Function of the Reproductive Organs. Vol. 111. N.. pp. I11-120. Am-Serono Symposia, Rome. Vigier, B.. , Magre, S.. Tmn. D.. and J~sso,N. (1987) Purifi bovine AMH induces a characteristic freemartin effect in fetal rat prospective ovaries exposed to i t in v i m .

I . , and Riggs. A. D.. (I’M)) Measurement by quantitative PCR of changes in HPRT, PGK-I, PGK-2. APRT. MTase. and Zfy gene transcripts during mouse spermatogenesis. Nucleic Acids Res. IX: 1255-1259. Singh, L.. Matsukuma. S.. and Jones. K. W. (1987) Testis development in a mouse with 10%of XY cells. Dev. Biol. 122287-290. Sutcliffe. M. J.. and Burgoyne. P. S. (1989) Analysis of the testes o f H-Y negative XOSxf mice suggests that the spermatogenesis gene (Spy) acts during the differentiation o f the A spermatogonia.

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